Bronchial responsiveness to histamine and methacholine measured with forced expirations and with the forced oscillation technique

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Bronchial responsiveness to histamine and methacholine measured with forced expirations and with the forced oscillation technique.

The objective of this study was to compare bronchial challenge tests with two substances [histamine (H) and methacholine (M)] and two methods of measuring the effect parameter FEV1 and pulmonary impedance [with the forced oscillation technique (FOT)] in order to determine which test is the shortest, and gives the least (drug) load to the patient. Furthermore, it was considered whether the resul...

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Methacholine responsiveness in infants assessed with low frequency forced oscillation and forced expiration techniques.

BACKGROUND The contribution of the pulmonary tissues to the mechanical behaviour of the respiratory system is well recognised. This study was undertaken to detect airway and lung tissue responses to inhaled methacholine (Mch) using the low frequency forced oscillation technique (LFOT). METHODS The respiratory system impedance (Zrs, 0.5-20 Hz) was determined in 17 asymptomatic infants. A model...

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Measurement of bronchial responsiveness by forced oscillation technique in occupational epidemiology.

The performance of the forced oscillation technique (FOT) in the assessment of bronchial responsiveness on the methacholine challenge test was compared with that of forced expiratory volume in one second (FEV1) in 119 active workers with normal baseline pulmonary function. Changes in resistance (delta R0%), frequency dependence of resistance (delta P) and resonant frequency (delta F%) determine...

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Association between respiratory impedance measured by forced oscillation technique and exacerbations in patients with COPD

Background It is well known that increased airflow limitation as measured by spirometry is associated with the risk of exacerbation in patients with COPD. The forced oscillation technique (FOT) is a noninvasive method used to assess respiratory impedance (resistance and reactance) with minimal patient cooperation required. The clinical utility of the FOT in assessing the risk of exacerbations o...

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ژورنال

عنوان ژورنال: Respiratory Medicine

سال: 1995

ISSN: 0954-6111

DOI: 10.1016/0954-6111(95)90007-1